
Kratom is not a controlled substance, but it may cause physical dependence. These may also cause kratom’s long-term risks that are similar to opioids, such as withdrawal.īenzodiazepines and opioids have additive effects on the central nervous system (CNS) when mixed together, which can create toxicity at previously low doses. Two chemicals in kratom, mitragynine and 7-α-hydroxymitragynine, cause analgesic (pain relief) effects. It is known that kratom acts on opioid receptors, much like opioids themselves. Why Mixing Kratom & Benzos Can Increase Health Risks

Withdrawal symptoms for both substances may include: Kratom withdrawal may look and feel like opioid withdrawal, while benzodiazepine withdrawal can also be difficult to handle. In serious cases, a SUD may lead to drug addiction and withdrawal when trying to come off the drug. This may be a sign of a substance use disorder, where continued drug use comes at the cost of your physical and mental health. Mixing kratom and benzodiazepines may mean you are not taking these substances as directed. However, they can interact with other substances, such as prescription opioids and kratom to cause an overdose. Toxicology reports showed that benzodiazepines were the third most common substance found in kratom overdose victims, after fentanyl and heroin.īenzodiazepines are difficult to overdose on their own, needing extremely high doses. Risk Of OverdoseĪ 2017 study by the CDC reported over 22% of kratom overdose deaths also involved benzodiazepines. It may also put you at risk of a kratom overdose. Mixing kratom and benzos can increase your chances of negative side effects from both substances. Use of kratom can cause drowsiness, sedation, constipation, nausea, and other opioid-like effects.īenzodiazepines are known to cause side effects in patients, including dry mouth, lightheadedness, dizziness, reduced blood pressure, and reduced concentration. None of these uses are medically approved for either substance, and may be signs of substance abuse. People may want to mix these substances to: Brands like Klonopin, Valium, and Xanax can reduce anxiety and suppress panic attacks in the short-term. In small doses, it can increase energy and alertness like a stimulant.īenzodiazepines are commonly prescribed to treat anxiety disorders. In high doses, it can reduce pain and increase euphoria like an opioid.

On its own, kratom is a pill, capsule, or extract that has effects similar to both opioids and stimulants. Like other forms of drug overdose, a kratom overdose can be fatal. Mixing kratom and benzos may also put you at risk for a kratom overdose.

Mixing these substances is usually not recommended by any doctor or medical professional. Mixing kratom and benzodiazepines can increase your risk of side effects, such as drowsiness, nausea, constipation, seizures, and hallucinations.
